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Wegovy vs. Zepbound: What Really Happens When You Switch
If you’ve lost 15% of your body weight on Wegovy, you might wonder—will switching to Zepbound help you lose another 20%? The short answer: no. The longer answer is more complicated.
I explain what actually happens when switching from Wegovy to Zepbound. While Wegovy targets the GLP-1 hormone, Zepbound works with both GLP-1 and GIP, which can help with appetite control and fat metabolism. But switching doesn’t automatically reset your weight loss. Most people won’t see another 20% weight loss—especially after losing a significant amount.
I also cover why weight loss slows due to metabolic adaptation—your body’s natural defense against further loss. For some, Zepbound can help break a plateau or improve appetite control. For others, the change might be minimal. This switch makes sense if you’ve plateaued, struggled with side effects, or need more help with cravings—but it’s not a magic fix.
Thanks for watching and always remember: small tweaks lead to massive peaks!
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📺 Watch These Next:
▪️ Watch This Before Taking Mounjaro
▪️ From Ozempic to Mounjaro
▪️ Muscle Loss with Ozempic, Wegovy & Mounjaro
▪️ Managing Nausea from Ozempic, Wegovy and Trulicity!
▪️ Ozempic: Stomach Paralysis Update
▪️ How to Switch from Ozempic (or Wegovy) to Mounjaro
▪️ Ozempic Paralyzed My Stomach
▪️ How to Inject Mounjaro: step-by-step tutorial
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🎯 Free Resources:
▪️ GLP-1/GIP Medication Info Sheet + 7-Day Food Journal
▪️ Total Daily Energy Expenditure (TDEE) Calculator – Find your optimal calorie intake
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🛒 Recommended Products for Your Weight-Loss Journey:
▪️ Managing Constipation
▪️ Managing Heartburn
▪️ Protein Bars & Supplements
▪️ Activity Trackers & Scales
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Live in Alberta? Come see me at my Pharmacist-led Obesity Clinic at Apothecare Pharmacy – http://apothecarerx.ca
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Dr. Dan
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